4Y3B
Crystal structure of C-terminal modified Tau peptide-hybrid 201D with 14-3-3sigma
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 2 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | C, D | ARG-THR-PRO-SEP-LEU-PRO-THR-[H][C@@]1(C(C2=CC=CC=C2)C3=CC=CC=C3)CCCN1C | polymer | 7 | 851.9 | 2 | UniProt (by SIFTS) (P10636) In PDB | Homo sapiens | |
| 3 | C | (2S)-2-(2-methoxyethyl)pyrrolidine | non-polymer | 129.2 | 1 | Chemie (49F) | |||
| 4 | water | water | 18.0 | 687 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 54789.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 129.2 | |
| All* | Total formula weight | 54918.8 |
