4WR7
Crystal structure of human carbonic anhydrase isozyme I with 2,3,5,6-Tetrafluoro-4-(propylthio)benzenesulfonamide.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Carbonic anhydrase 1 | polymer | 260 | 28835.1 | 2 | UniProt (P00915) Pfam (PF00194) In PDB | Homo sapiens (Human) | Carbonate dehydratase I,Carbonic anhydrase B,CAB,Carbonic anhydrase I,CA-I |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | 2,3,5,6-tetrafluoro-4-(propylsulfanyl)benzenesulfonamide | non-polymer | 303.3 | 2 | Chemie (3TV) | |||
| 4 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | A, B | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 6 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 7 | water | water | 18.0 | 516 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 260 (UniProt: P00915)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57670.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1085.8 | |
| All* | Total formula weight | 58756.0 |
