4WQN
Crystal structure of N6-methyladenosine RNA reader YTHDF2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | YTH domain-containing family protein 2 | polymer | 173 | 19987.6 | 2 | UniProt (Q9Y5A9) Pfam (PF04146) In PDB | Homo sapiens (Human) | N6-methyladenosine RNA reader YTHDF2,CLL-associated antigen KW-14,High-glucose-regulated protein 8,Renal carcinoma antigen NY-REN-2 |
| 2 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 175 | Chemie (HOH) |
Sequence modifications
A, B: 383 - 553 (UniProt: Q9Y5A9)
| PDB | External Database | Details |
|---|---|---|
| Gly 381 | - | expression tag |
| Ser 382 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39975.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 216.2 | |
| All* | Total formula weight | 40191.4 |
