4UST

Crystal structure of human soluble Adenylyl Cyclase with pyrophosphate resulting from soaking with GTP and Magnesium

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	ADENYLATE CYCLASE TYPE 10	polymer	475	54269.7	1	UniProt (Q96PN6) Pfam (PF00211) In PDB	HOMO SAPIENS (HUMAN)	AH-RELATED PROTEIN, ADENYLATE CYCLASE HOMOLOG, GERM CELL SO LUBLE ADENYLYL CYCLASE, HSAC, SAC, TESTICULAR SOLUBLE ADENYLYL CYC LASE, SOLUBLE ADENYLYL CYCLASE
2	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	A	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	A	PYROPHOSPHATE 2-	non-polymer		176.0	1	Chemie (POP)
5	A	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
6	A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
7	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8		water	water		18.0	221	Chemie (HOH)

Sequence modifications

A: 1 - 469 (UniProt: Q96PN6)

PDB	External Database	Details
His 470	-	expression tag
His 471	-	expression tag
His 472	-	expression tag
His 473	-	expression tag
His 474	-	expression tag
His 475	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	54269.7
Non-Polymers*	Number of molecules	8
	Total formula weight	546.4
All*	Total formula weight	54816.1

*Water molecules are not included.