4U7U

Crystal structure of RNA-guided immune Cascade complex from E.coli

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, M	CRISPR system Cascade subunit CasA	polymer	502	55965.0	2	UniProt (Q46901) Pfam (PF09481) In PDB	Escherichia coli K12	CRISPR type I-E/Ecoli-associated protein CasA/Cse1,CRISPR-associated protein CasA/Cse1
2	B, C, N, O	CRISPR system Cascade subunit CasB	polymer	160	18728.5	4	UniProt (P76632) Pfam (PF09485) In PDB	Escherichia coli K12
3	D, P	CRISPR system Cascade subunit CasE	polymer	201	22581.3	2	UniProt (Q46897) Pfam (PF08798) In PDB	Escherichia coli K12	CasE endoRNase,crRNA endonuclease
4	E, F, G, H, I...	CRISPR system Cascade subunit CasC	polymer	363	40071.4	12	UniProt (Q46899) Pfam (PF09344) In PDB	Escherichia coli K12
5	K, W	CRISPR system Cascade subunit CasD	polymer	224	25239.8	2	UniProt (Q46898) Pfam (PF09704) In PDB	Escherichia coli K12
6	L, X	crRNA	polymer	61	19634.6	2	GenBank (882596)	Escherichia coli str. K-12 substr. MG1655

Sequence modifications

D, P: 1 - 199 (UniProt: Q46897)

PDB	External Database	Details
Ala -1	-	expression tag
Trp 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	802612.3
All*	Total formula weight	802612.3

*Water molecules are not included.