4RVT
MAP4K4 in complex with a pyridin-2(1H)-one derivative
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Mitogen-activated protein kinase kinase kinase kinase 4 | polymer | 328 | 37535.9 | 2 | UniProt (O95819) Pfam (PF00069) In PDB | Homo sapiens (human) | HPK/GCK-like kinase HGK, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, Nck-interacting kinase |
2 | A | 3-hexanoyl-4-hydroxy-5-(4-hydroxyphenyl)pyridin-2(1H)-one | non-polymer | 301.3 | 1 | Chemie (3XM) | |||
3 | A | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
4 | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 325 (UniProt: O95819)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 75071.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 496.6 | |
All* | Total formula weight | 75568.3 |