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4RHU

Crystal structures of Mycobacterium tuberculosis 6-oxopurine phosphoribosyltransferase which is a potential target for drug development against this disease

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...Hypoxanthine-guanine phosphoribosyltransferase Hptpolymer20122140.96UniProt (I6YCM5)
Pfam (PF00156)
UniProt (by SIFTS) (P9WHQ9)
In PDB
Mycobacterium tuberculosis
2A, B{[(2R)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid)non-polymer441.32Chemie (3QE)
3A, B, C, D, E...MAGNESIUM IONnon-polymer24.38Chemie (MG)
4C, D, E, F{[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid)non-polymer441.34Chemie (45T)
5waterwater18.084Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight132845.5
Non-Polymers*Number of molecules14
Total formula weight2842.1
All*Total formula weight135687.6
*Water molecules are not included.

220472

PDB entries from 2024-05-29

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