4PR4
Human Aldose Reductase complexed with Schl7802 at 1.06 A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Aldose reductase | polymer | 315 | 35767.1 | 1 | UniProt (P15121) Pfam (PF00248) In PDB | Homo sapiens (human) | AR, Aldehyde reductase, Aldo-keto reductase family 1 member B1 |
| 2 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | A | 3-(3'-nitrobiphenyl-3-yl)propanoic acid | non-polymer | 271.3 | 1 | Chemie (2W8) | |||
| 4 | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
A: 1 - 315 (UniProt: P15121)
| PDB | External Database | Details |
|---|---|---|
| Ile 4 | Leu 5 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35767.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1014.7 | |
| All* | Total formula weight | 36781.8 |
