4PJA

Structure of human MR1-5-OP-RU in complex with human MAIT B-B10 TCR

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Major histocompatibility complex class I-related gene protein	polymer	271	31711.7	2	UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) In PDB	Homo sapiens (Human)	MHC class I-related gene protein,Class I histocompatibility antigen-like protein
2	B, D	Beta-2-microglobulin	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (Human)
3	E, G	TCR-alpha	polymer	205	22879.4	2		Homo sapiens (Human)
4	F, H	TCR-beta	polymer	245	27642.7	2		Homo sapiens (Human)
5	A, C	1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol	non-polymer		316.3	2	Chemie (2LJ)
6	B	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
7		water	water		18.0	660	Chemie (HOH)

Sequence modifications

A, C: 1 - 270 (UniProt: Q95460)

PDB	External Database	Details
Met 0	-	initiating methionine
Ser 261	Cys 283	engineered mutation

B, D: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	188226.2
Non-Polymers*	Number of molecules	3
	Total formula weight	724.7
All*	Total formula weight	188950.9

*Water molecules are not included.