4OZT
crystal structure of the ligand binding domains of the Bovicola ovis ecdysone receptor EcR/USP heterodimer (PonA crystal)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | E | Ecdysone receptor | polymer | 238 | 27482.6 | 1 | UniProt (E0VVT4) Pfam (PF00104) In PDB | Pediculus humanus subsp. corporis (Body louse) | |
2 | U | Retinoid X receptor | polymer | 195 | 21977.5 | 1 | UniProt (E0VFQ5) Pfam (PF00104) In PDB | Pediculus humanus subsp. corporis (Body louse) | |
3 | E | 2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE | non-polymer | 464.6 | 1 | Chemie (P1A) | |||
4 | U | N-ETHYLMALEIMIDE | non-polymer | 125.1 | 1 | Chemie (NEQ) | |||
5 | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
E: 281 - 518 (UniProt: E0VVT4)
U: 196 - 390 (UniProt: E0VFQ5)
PDB | External Database | Details |
---|---|---|
Thr 316 | Ala 316 | conflict |
Ala 472 | Arg 472 | conflict |
PDB | External Database | Details |
---|---|---|
Ser 207 | Thr 233 | conflict |
Ser 302 | Cys 328 | conflict |
Lys 373 | Arg 399 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 49460.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 589.8 | |
All* | Total formula weight | 50049.9 |