4OS8
Three-dimensional structure of the C65A-W54F-W112F triple mutant of Human lipocalin-type Prostaglandin D Synthase apo-form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Prostaglandin-H2 D-isomerase | polymer | 190 | 20939.6 | 2 | UniProt (P41222) Pfam (PF00061) In PDB | Homo sapiens (human) | Beta-trace protein, Cerebrin-28, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, Prostaglandin-D2 synthase, PGD2 synthase, PGDS, PGDS2 |
| 2 | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 190 (UniProt: P41222)
| PDB | External Database | Details |
|---|---|---|
| Phe 54 | Trp 54 | engineered mutation |
| Ala 65 | Cys 65 | engineered mutation |
| Phe 112 | Trp 112 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41879.3 | |
| All* | Total formula weight | 41879.3 |
