4OPT
Constructing tailored isoprenoid products by structure-guided modification of geranylgeranyl reductase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Conserved Archaeal protein | polymer | 453 | 50887.0 | 1 | UniProt (Q4JA33) Pfam (PF01266) In PDB | Sulfolobus acidocaldarius | Geranylgeranyl Reductase |
2 | A | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE | non-polymer | 787.6 | 1 | Chemie (FDA) | |||
3 | A | GERANYLGERANYL DIPHOSPHATE | non-polymer | 450.4 | 1 | Chemie (GRG) | |||
4 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
5 | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A: 1 - 452 (UniProt: Q4JA33)
PDB | External Database | Details |
---|---|---|
His 0 | - | EXPRESSION TAG |
Phe 206 | Ile 206 | ENGINEERED MUTATION |
His 377 | Leu 377 | ENGINEERED MUTATION |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 50887.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1334.1 | |
All* | Total formula weight | 52221.1 |