4MRI
Human brain aspartoacylase mutant F295S complex with intermediate analog (N-phosphonomethyl-L-aspartate)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Aspartoacylase | polymer | 313 | 35724.0 | 2 | UniProt (P45381) Pfam (PF04952) In PDB | Homo sapiens (human) | Aminoacylase-2, ACY-2 |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID | non-polymer | 211.1 | 2 | Chemie (AS9) | |||
| 4 | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 313 (UniProt: P45381)
| PDB | External Database | Details |
|---|---|---|
| Ser 295 | Phe 295 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71448.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 553.0 | |
| All* | Total formula weight | 72001.0 |
