4MG9
Crystal structure of hERa-LBD (Y537S) in complex with butylparaben
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Estrogen receptor | polymer | 255 | 29054.2 | 1 | UniProt (P03372) Pfam (PF00104) In PDB | Homo sapiens (human) | ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1 |
2 | B | Estrogen receptor | polymer | 255 | 29086.2 | 1 | UniProt (P03372) Pfam (PF00104) In PDB | Homo sapiens (human) | ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1 |
3 | F, G | Nuclear receptor coactivator 1 | polymer | 13 | 1591.9 | 2 | UniProt (Q15788) In PDB | Homo sapiens | NCoA-1, Class E basic helix-loop-helix protein 74, bHLHe74, Protein Hin-2, RIP160, Renal carcinoma antigen NY-REN-52, Steroid receptor coactivator 1, SRC-1 |
4 | A, B | butyl 4-hydroxybenzoate | non-polymer | 194.2 | 2 | Chemie (27K) | |||
5 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
6 | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
A: 302 - 552 (UniProt: P03372)
B: 302 - 552 (UniProt: P03372)
PDB | External Database | Details |
---|---|---|
Gly 298 | - | expression tag |
Ser 299 | - | expression tag |
His 300 | - | expression tag |
Met 301 | - | expression tag |
Ser 537 | Tyr 537 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 298 | - | expression tag |
Ser 299 | - | expression tag |
His 300 | - | expression tag |
Met 301 | - | expression tag |
Ser 537 | Tyr 537 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 61324.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 572.6 | |
All* | Total formula weight | 61896.8 |