4MD4
Immune Receptor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HLA class II histocompatibility antigen, DR alpha chain | polymer | 189 | 21919.6 | 1 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) In PDB | Homo sapiens (human) | MHC class II antigen DRA |
2 | B | HLA class II histocompatibility antigen, DRB1-4 beta chain | polymer | 200 | 23224.6 | 1 | UniProt (P13760) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) In PDB | Homo sapiens (human) | MHC class II antigen DRB1*4, DR-4, DR4 |
3 | C | Aggrecan core protein | polymer | 15 | 1802.9 | 1 | UniProt (P16112) In PDB | Homo sapiens | Cartilage-specific proteoglycan core protein, CSPCP, Chondroitin sulfate proteoglycan core protein 1, Chondroitin sulfate proteoglycan 1, Aggrecan core protein 2 |
4 | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
5 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
6 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
7 | water | water | 18.0 | 470 | Chemie (HOH) |
Sequence modifications
A: 1 - 181 (UniProt: P01903)
B: 1 - 190 (UniProt: P13760)
C: 1 - 15 (UniProt: P16112)
PDB | External Database | Details |
---|---|---|
Thr 182 | - | expression tag |
Ser 183 | - | expression tag |
Gly 184 | - | expression tag |
Asp 185 | - | expression tag |
Asp 186 | - | expression tag |
Asp 187 | - | expression tag |
Asp 188 | - | expression tag |
Lys 189 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Thr 191 | - | expression tag |
Gly 192 | - | expression tag |
Gly 193 | - | expression tag |
Asp 194 | - | expression tag |
Asp 195 | - | expression tag |
Asp 196 | - | expression tag |
Asp 197 | - | expression tag |
Lys 198 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Tyr 4 | Gly 92 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 46947.1 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 628.6 | |
All* | Total formula weight | 48000.1 |