4M9V

Zfp57 mutant (E182Q) in complex with 5-carboxylcytosine DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	DNA (5'-D(*TP*AP*TP*TP*GP*CP*(5CM)P*GP*CP*AP*G)-3')	polymer	11	3363.2	2
2	B, E	DNA (5'-D(*AP*CP*TP*GP*(1CC)P*GP*GP*CP*AP*AP*T)-3')	polymer	11	3402.2	2
3	C, F	Zinc finger protein 57	polymer	64	7376.4	2	UniProt (Q8C6P8) Pfam (PF00096) In PDB	Mus musculus (mouse)	Zfp-57
4	B, C, E, F	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	4	Chemie (MPD)
5	B, C, E	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
6	B, E	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
7	C, F	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
8		water	water		18.0	472	Chemie (HOH)

Sequence modifications

C, F: 137 - 195 (UniProt: Q8C6P8)

PDB	External Database	Details
Gly 132	-	expression tag
Pro 133	-	expression tag
Leu 134	-	expression tag
Gly 135	-	expression tag
Ser 136	-	expression tag
Gln 182	Glu 182	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	28283.7
Non-Polymers*	Number of molecules	14
	Total formula weight	1050.7
All*	Total formula weight	29334.4

*Water molecules are not included.