4M2S

Corrected Structure of Mouse P-glycoprotein bound to QZ59-RRR

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Multidrug resistance protein 1A	polymer	1282	141677.7	2	UniProt (P21447) Pfam (PF00664) Pfam (PF00005) In PDB	Mus musculus (mouse)	ATP-binding cassette sub-family B member 1A, MDR1A, Multidrug resistance protein 3, P-glycoprotein 3
2	A, B	(4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione	non-polymer		687.4	2	Chemie (0JZ)

Sequence modifications

A, B: 1 - 1276 (UniProt: P21447)

PDB	External Database	Details
Gln 83	Asn 83	conflict
Gln 87	Asn 87	conflict
Gln 90	Asn 90	conflict
His 1277	-	expression tag
His 1278	-	expression tag
His 1279	-	expression tag
His 1280	-	expression tag
His 1281	-	expression tag
His 1282	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	283355.4
Non-Polymers*	Number of molecules	2
	Total formula weight	1374.8
All*	Total formula weight	284730.2

*Water molecules are not included.