4KZM

Crystal Structure of TR3 LBD S553A Mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A	Nuclear receptor subfamily 4 group A member 1	polymer	257	28729.3	2	UniProt (P22736) Pfam (PF00104) In PDB	Homo sapiens (human)	Early response protein NAK1, Nuclear hormone receptor NUR/77, Nur77, Orphan nuclear receptor HMR, Orphan nuclear receptor TR3, ST-59, Testicular receptor 3
2	B, A	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
3		water	water		18.0	152	Chemie (HOH)

Sequence modifications

B, A: 351 - 598 (UniProt: P22736)

PDB	External Database	Details
Met 350	-	expression tag
Ala 553	Ser 553	engineered mutation
Leu 599	-	expression tag
Glu 600	-	expression tag
His 601	-	expression tag
His 602	-	expression tag
His 603	-	expression tag
His 604	-	expression tag
His 605	-	expression tag
His 606	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57458.6
Non-Polymers*	Number of molecules	3
	Total formula weight	276.3
All*	Total formula weight	57734.9

*Water molecules are not included.