4KLZ
Inhibition of Small GTPases by Stabilization of the GDP Complex, a Novel Approach applied to Rit1, a Target for Rheumatoid Arthritis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | GTP-binding protein Rit1 | polymer | 173 | 20085.8 | 1 | UniProt (Q92963) Pfam (PF00071) In PDB | Homo sapiens (human) | Ras-like protein expressed in many tissues, Ras-like without CAAX protein 1 |
| 2 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A: 19 - 189 (UniProt: Q92963)
| PDB | External Database | Details |
|---|---|---|
| Gly 17 | - | expression tag |
| Ser 18 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20085.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 467.5 | |
| All* | Total formula weight | 20553.3 |
