4JIF

Co-crystal structure of ICAP1 PTB domain in complex with a KRIT1 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Integrin beta-1-binding protein 1	polymer	154	16909.0	1	UniProt (O14713) Pfam (PF10480) In PDB	Homo sapiens (human)	Integrin cytoplasmic domain-associated protein 1, ICAP-1
2	B	Krev interaction trapped protein 1	polymer	34	3726.2	1	UniProt (O00522) In PDB	Homo sapiens (human)	Krev interaction trapped 1, Cerebral cavernous malformations 1 protein
3		water	water		18.0	111	Chemie (HOH)

Sequence modifications

A: 49 - 200 (UniProt: O14713)

PDB	External Database	Details
Gly 47	-	expression tag
Ser 48	-	expression tag

B: 170 - 198 (UniProt: O00522)

PDB	External Database	Details
Gly 165	-	expression tag
Pro 166	-	expression tag
Leu 167	-	expression tag
Gly 168	-	expression tag
Ser 169	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	20635.3
All*	Total formula weight	20635.3

*Water molecules are not included.