4IZA
Structure of Dually Phosphorylated ERK2 bound to the PEA-15 Death Effector Domain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Mitogen-activated protein kinase 1 | polymer | 356 | 41258.2 | 2 | UniProt (P28482) Pfam (PF00069) In PDB | Homo sapiens (human) | MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2 |
2 | B | Astrocytic phosphoprotein PEA-15 | polymer | 97 | 11238.5 | 1 | UniProt (Q15121) Pfam (PF01335) In PDB | Homo sapiens (human) | 15 kDa phosphoprotein enriched in astrocytes, Phosphoprotein enriched in diabetes, PED |
3 | water | water | 18.0 | 633 | Chemie (HOH) |
Sequence modifications
A, C: 8 - 360 (UniProt: P28482)
B: 1 - 96 (UniProt: Q15121)
PDB | External Database | Details |
---|---|---|
Gly 5 | - | EXPRESSION TAG |
Pro 6 | - | EXPRESSION TAG |
Gly 7 | - | EXPRESSION TAG |
PDB | External Database | Details |
---|---|---|
Gly 0 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 93754.8 | |
All* | Total formula weight | 93754.8 |