4IKM

X-ray structure of CARD8 CARD domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Maltose-binding periplasmic protein, Caspase recruitment domain-containing protein 8	polymer	469	53368.1	1	UniProt (P0AEX9) UniProt (Q9Y2G2) Pfam (PF01547) Pfam (PF00619) In PDB	Escherichia coli (human)	MBP, MMBP, Maltodextrin-binding protein, Apoptotic protein NDPP1, CARD-inhibitor of NF-kappa-B-activating ligand, CARDINAL, DACAR, Tumor up-regulated CARD-containing antagonist of CASP9, TUCAN
2	B	alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose	branched		342.3	1	In PDB BIRD (PRD_900001) GlyTouCan (G07411ON)		alpha-maltose
3	A	IODIDE ION	non-polymer		126.9	2	Chemie (IOD)
4	A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5		water	water		18.0	69	Chemie (HOH)

Sequence modifications

A: 2 - 367 (UniProt: P0AEX9)

PDB	External Database	Details
Met 1	-	expression tag
Ala 83	Asp 108	conflict
Ala 84	Lys 109	conflict
Ala 173	Glu 198	conflict
Ala 174	Asn 199	conflict
Ala 240	Lys 265	conflict
Ala 360	Glu 385	conflict
Ala 363	Lys 388	conflict
Ala 364	Asp 389	conflict
Asn 368	-	expression tag
Ala 369	-	expression tag
Val 370	-	expression tag
Asp 371	-	expression tag

A: 372 - 458 (UniProt: Q9Y2G2)

PDB	External Database	Details
Ala 459	-	expression tag
Ala 460	-	expression tag
Ala 461	-	expression tag
Leu 462	-	expression tag
Glu 463	-	expression tag
His 464	-	expression tag
His 465	-	expression tag
His 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag
His 469	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	53368.1
Branched	Number of molecules	1
	Total formula weight	342.3
Non-Polymers*	Number of molecules	4
	Total formula weight	377.9
All*	Total formula weight	54088.3

*Water molecules are not included.