4GRR
characterization of N- and C- terminus mutants of human MIF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Macrophage migration inhibitory factor | polymer | 116 | 12497.2 | 3 | UniProt (P14174) Pfam (PF01187) In PDB | Homo sapiens (human) | MIF, Glycosylation-inhibiting factor, GIF, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase |
| 2 | A, C | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | A, B, C | CHLORIDE ION | non-polymer | 35.5 | 11 | Chemie (CL) | |||
| 4 | B | (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one | non-polymer | 231.3 | 1 | Chemie (AVR) | |||
| 5 | water | water | 18.0 | 491 | Chemie (HOH) |
Sequence modifications
A, B, C: 4 - 116 (UniProt: P14174)
| PDB | External Database | Details |
|---|---|---|
| Pro 1 | - | insertion |
| Ala 2 | - | insertion |
| Ala 3 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37491.6 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1101.6 | |
| All* | Total formula weight | 38593.2 |
