4FOI
Crystal Structure of recombinant human Hexokinase type I mutant D413N with Glucose 1,6-bisphosphate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Hexokinase-1 | polymer | 917 | 102624.1 | 2 | UniProt (P19367) Pfam (PF00349) Pfam (PF03727) In PDB | Homo sapiens (human) | Brain form hexokinase, Hexokinase type I, HK I |
2 | A, B | beta-D-glucopyranose | non-polymer | 180.2 | 4 | Chemie (BGC) | |||
3 | A, B | 1,6-di-O-phosphono-alpha-D-glucopyranose | non-polymer | 339.1 | 4 | Chemie (G16) | |||
4 | A, B | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
5 | A, B | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
6 | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 917 (UniProt: P19367)
PDB | External Database | Details |
---|---|---|
Asn 413 | Asp 413 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 205248.1 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 2553.3 | |
All* | Total formula weight | 207801.4 |