4EZ5

CDK6 (monomeric) in complex with inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cyclin-dependent kinase 6	polymer	307	35019.2	1	UniProt (Q00534) Pfam (PF00069) In PDB	Homo sapiens (human)	Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE
2	A	{5-[4-(dimethylamino)piperidin-1-yl]-1H-imidazo[4,5-b]pyridin-2-yl}[2-(isoquinolin-4-yl)pyridin-4-yl]methanone	non-polymer		477.6	1	Chemie (0RS)

Sequence modifications

A: 1 - 301 (UniProt: Q00534)

PDB	External Database	Details
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	35019.2
Non-Polymers*	Number of molecules	1
	Total formula weight	477.6
All*	Total formula weight	35496.8

*Water molecules are not included.