4ESG

X-ray structure of WDR5-MLL1 Win motif peptide binary complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	WD repeat-containing protein 5	polymer	312	34303.9	2	UniProt (P61964) Pfam (PF00400) In PDB	Homo sapiens (human)	BMP2-induced 3-kb gene protein
2	C, D	Histone-lysine N-methyltransferase MLL	polymer	17	1884.1	2	UniProt (Q03164) In PDB	Homo sapiens	ALL-1, CXXC-type zinc finger protein 7, Lysine N-methyltransferase 2A, KMT2A, Trithorax-like protein, Zinc finger protein HRX, MLL cleavage product N320, N-terminal cleavage product of 320 kDa, p320, MLL cleavage product C180, C-terminal cleavage product of 180 kDa, p180
3		water	water		18.0	627	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	72376.0
All*	Total formula weight	72376.0

*Water molecules are not included.