4D4U

Crystal Structure of Fucose binding lectin from Aspergillus Fumigatus (AFL) in complex with LewisY tetrasaccharide.

Replaces:  4AH5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	FUCOSE-SPECIFIC LECTIN FLEA	polymer	315	34628.5	2	UniProt (Q4WW81) Pfam (PF07938) In PDB	ASPERGILLUS FUMIGATUS	AFL
2	C, D, G, H	alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		529.5	4	In PDB BIRD (PRD_900036) GlyTouCan (G61459JW)		H type 2 antigen, beta anomer
3	E, F, I	alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose	branched		675.6	3	In PDB BIRD (PRD_900124) GlyTouCan (G82236PZ)		Lewis Y antigen, alpha anomer
4	J	alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose	branched		326.3	1	In PDB GlyTouCan (G00068MO)
5	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	A, B	alpha-L-fucopyranose	non-polymer		164.2	2	Chemie (FUC)
7		water	water		18.0	412	Chemie (HOH)

Sequence modifications

A, B: 1 - 315 (UniProt: Q4WW81)

PDB	External Database	Details
Ser 20	Leu 20	conflict
Cys 111	Arg 111	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	69256.9
Branched	Number of molecules	8
	Total formula weight	4471.1
Non-Polymers*	Number of molecules	4
	Total formula weight	512.5
All*	Total formula weight	74240.6

*Water molecules are not included.