4D3Q

crystal structure of point mutated DUSP19 (R156A)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	DUAL SPECIFICITY PROTEIN PHOSPHATASE 19	polymer	147	16133.3	2	UniProt (Q8WTR2) Pfam (PF00782) In PDB	HOMO SAPIENS (HUMAN)	DUAL SPECIFICITY PHOSPHATASE TS-DSP1, LOW MOLECULAR WEIGHT DUAL SPECIFICITY PHOSPHATASE 3, LMW-DSP3, PROTEIN PHOSPHATASE SKRP 1, STRESS-ACTIVATED PROTEIN KINASE PATHWAY-REGULATING PHOSPHATASE 1, SAPK PATHWAY-REGULATING PHOSPHATASE 1
2	A, B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3		water	water		18.0	159	Chemie (HOH)

Sequence modifications

A, B: 65 - 205 (UniProt: Q8WTR2)

PDB	External Database	Details
Gly 59	-	expression tag
Ser 60	-	expression tag
His 61	-	expression tag
Met 62	-	expression tag
Ala 63	-	expression tag
Ser 64	-	expression tag
Ser 150	Cys 150	engineered mutation
Ala 156	Arg 156	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	32266.6
Non-Polymers*	Number of molecules	2
	Total formula weight	192.1
All*	Total formula weight	32458.7

*Water molecules are not included.