4CY1
Crystal structure of the KANSL1-WDR5 complex.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | WD REPEAT-CONTAINING PROTEIN 5 | polymer | 316 | 34620.3 | 2 | UniProt (P61964) Pfam (PF00400) In PDB | HOMO SAPIENS (HUMAN) | BMP2-INDUCED 3-KB GENE PROTEIN |
2 | C, D | KAT8 REGULATORY NSL COMPLEX SUBUNIT 1 | polymer | 15 | 1610.8 | 2 | UniProt (Q7Z3B3) In PDB | HOMO SAPIENS | KANSL1, MLL1/MLL COMPLEX SUBUNIT KANSL1, MSL1 HOMOLOG 1, HMSL1V1, NSL COMPLEX PROTEIN NSL1, NON-SPECIFIC LETHAL 1 HOMOLOG |
3 | A, B, D | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
4 | water | water | 18.0 | 321 | Chemie (HOH) |
Sequence modifications
A, B: 23 - 334 (UniProt: P61964)
C, D: 585 - 598 (UniProt: Q7Z3B3)
PDB | External Database | Details |
---|---|---|
Met 21 | - | expression tag |
Gly 22 | - | expression tag |
Gly 335 | - | expression tag |
Ala 336 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Tyr 599 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 72462.2 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 276.3 | |
All* | Total formula weight | 72738.5 |