4CPH
trans-divalent streptavidin with love-hate ligand 4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | STREPTAVIDIN | polymer | 127 | 13250.3 | 2 | UniProt (P22629) Pfam (PF01382) In PDB | STREPTOMYCES AVIDINII | |
2 | B, C | STREPTAVIDIN | polymer | 133 | 14056.0 | 2 | UniProt (P22629) Pfam (PF01382) In PDB | STREPTOMYCES AVIDINII | |
3 | B, C | 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4- d]imidazolidin-4-yl]-N'-{2,6-bis[4-(morpholine-4- sulfonyl)phenyl]phenyl}pentanehydrazide | non-polymer | 785.0 | 2 | Chemie (LH4) | |||
4 | water | water | 18.0 | 254 | Chemie (HOH) |
Sequence modifications
A, D: 13 - 139 (UniProt: P22629)
B, C: 13 - 139 (UniProt: P22629)
PDB | External Database | Details |
---|---|---|
Ala 23 | Asn 47 | engineered mutation |
Asp 27 | Ser 51 | engineered mutation |
Ala 45 | Ser 69 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Glu 140 | - | expression tag |
Glu 141 | - | expression tag |
Glu 142 | - | expression tag |
Glu 143 | - | expression tag |
Glu 144 | - | expression tag |
Glu 145 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 54612.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1569.9 | |
All* | Total formula weight | 56182.6 |