4CLZ
Crystal structure of human soluble Adenylyl Cyclase with Inhibitor 4, 4'-Diisothiocyano-2,2'-stilbenedisulfonic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | ADENYLATE CYCLASE TYPE 10 | polymer | 475 | 54269.7 | 1 | UniProt (Q96PN6) Pfam (PF00211) In PDB | HOMO SAPIENS (HUMAN) | AH-RELATED PROTEIN, ADENYLATE CYCLASE HOMOLOG, GERM CELL SOLUBLE ADENYLYL CYCLASE, HSAC, SAC, TESTICULAR SOLUBLE ADENYLYL CYCLASE, SOLUBLE ADENYLYL CYCLASE |
| 2 | A | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 5 | A | 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid | non-polymer | 454.5 | 3 | Chemie (4DS) | |||
| 6 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 7 | water | water | 18.0 | 283 | Chemie (HOH) |
Sequence modifications
A: 1 - 469 (UniProt: Q96PN6)
| PDB | External Database | Details |
|---|---|---|
| His 470 | - | expression tag |
| His 471 | - | expression tag |
| His 472 | - | expression tag |
| His 473 | - | expression tag |
| His 474 | - | expression tag |
| His 475 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54269.7 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2260.6 | |
| All* | Total formula weight | 56530.2 |
