4CLT

Crystal structure of human soluble Adenylyl Cyclase with adenosine-3', 5'-cyclic-monophosphate and pyrophosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	ADENYLATE CYCLASE TYPE 10	polymer	475	54269.7	1	UniProt (Q96PN6) Pfam (PF00211) In PDB	HOMO SAPIENS (HUMAN)	AH-RELATED PROTEIN, ADENYLATE CYCLASE HOMOLOG, GERM CELL SOLUBLE ADENYLYL CYCLASE, HSAC, SAC, TESTICULAR SOLUBLE ADENYLYL CYCLASE, SOLUBLE ADENYLYL CYCLASE
2	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	A	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	non-polymer		329.2	2	Chemie (CMP)
4	A	PYROPHOSPHATE 2-	non-polymer		176.0	1	Chemie (POP)
5	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6	A	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
7		water	water		18.0	106	Chemie (HOH)

Sequence modifications

A: 1 - 469 (UniProt: Q96PN6)

PDB	External Database	Details
His 470	-	expression tag
His 471	-	expression tag
His 472	-	expression tag
His 473	-	expression tag
His 474	-	expression tag
His 475	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	54269.7
Non-Polymers*	Number of molecules	6
	Total formula weight	956.2
All*	Total formula weight	55225.9

*Water molecules are not included.