4CLK

Crystal structure of human soluble Adenylyl Cyclase in complex with alpha,beta-methyleneadenosine-5'-triphosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	ADENYLATE CYCLASE TYPE 10	polymer	475	54269.7	1	UniProt (Q96PN6) Pfam (PF00211) In PDB	HOMO SAPIENS (HUMAN)	AH-RELATED PROTEIN, ADENYLATE CYCLASE HOMOLOG, GERM CELL SOLUBLE ADENYLYL CYCLASE, HSAC, SAC, TESTICULAR SOLUBLE ADENYLYL CYCLASE, SOLUBLE ADENYLYL CYCLASE
2	A	DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER	non-polymer		505.2	1	Chemie (APC)
3	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	A	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
5	A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
6	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
7		water	water		18.0	168	Chemie (HOH)

Sequence modifications

A: 1 - 469 (UniProt: Q96PN6)

PDB	External Database	Details
His 470	-	expression tag
His 471	-	expression tag
His 472	-	expression tag
His 473	-	expression tag
His 474	-	expression tag
His 475	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	54269.7
Non-Polymers*	Number of molecules	7
	Total formula weight	889.1
All*	Total formula weight	55158.7

*Water molecules are not included.