4CK9
STEROL 14-ALPHA DEMETHYLASE (CYP51)FROM TRYPANOSOMA CRUZI IN COMPLEX WITH (S)-1-(4-chlorophenyl)-2-(1H-imidazol-1-yl)ethyl 4- isopropylphenylcarbamate (LFT)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | STEROL 14-ALPHA DEMETHYLASE | polymer | 460 | 52552.9 | 1 | UniProt (Q7Z1V1) Pfam (PF00067) In PDB | TRYPANOSOMA CRUZI | TC14DM, CYTOCHROME P450 51 |
| 2 | A | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | A | (1S)-1-(4-chlorophenyl)-2-(1H-imidazol-1-yl)ethyl [4-(propan-2-yl)phenyl]carbamate | non-polymer | 383.9 | 1 | Chemie (LFT) | |||
| 4 | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence modifications
A: 32 - 481 (UniProt: Q7Z1V1)
| PDB | External Database | Details |
|---|---|---|
| Ala 28 | - | expression tag |
| Lys 29 | - | expression tag |
| Lys 30 | - | expression tag |
| Thr 31 | - | expression tag |
| His 482 | - | expression tag |
| His 483 | - | expression tag |
| His 484 | - | expression tag |
| His 485 | - | expression tag |
| His 486 | - | expression tag |
| His 487 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52552.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1000.4 | |
| All* | Total formula weight | 53553.3 |
