4BL1

Crystal structure of unphosphorylated Maternal Embryonic Leucine zipper Kinase (MELK) in complex with AMP-PNP

Replaces:  3ZGW

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE	polymer	347	40220.5	1	UniProt (Q14680) Pfam (PF00069) Pfam (PF21594) In PDB	HOMO SAPIENS (HUMAN)	HMELK, PROTEIN KINASE EG3, PEG3 KINASE, PROTEIN KINASE PK38, HPK38, TYROSINE-PROTEIN KINASE MELK
2	A	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP)
3		water	water		18.0	47	Chemie (HOH)

Sequence modifications

A: 2 - 340 (UniProt: Q14680)

PDB	External Database	Details
Gly 0	-	expression tag
Pro 1	-	expression tag
His 341	-	expression tag
His 342	-	expression tag
His 343	-	expression tag
His 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	40220.5
Non-Polymers*	Number of molecules	1
	Total formula weight	506.2
All*	Total formula weight	40726.7

*Water molecules are not included.