4AWB
Crystal structure of active legumain in complex with AAN-CMK
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | LEGUMAIN | polymer | 284 | 32273.2 | 2 | UniProt (Q99538) Pfam (PF01650) In PDB | HOMO SAPIENS (HUMAN) | ASPARAGINYL ENDOPEPTIDASE, PROTEASE\, CYSTEINE 1 |
| 2 | I, J | Z-ALA-ALA-AZAASN-CHLOROMETHYLKETONE | polymer | 5 | 460.3 | 2 | BIRD (PRD_002087) | SYNTHETIC CONSTRUCT | |
| 3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 4 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | A, B | MERCURY (II) ION | non-polymer | 200.6 | 4 | Chemie (HG) | |||
| 6 | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 309 (UniProt: Q99538)
| PDB | External Database | Details |
|---|---|---|
| Gln 263 | Asn 263 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 65467.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2321.7 | |
| All* | Total formula weight | 67788.8 |
