4A6A

A115V variant of dCTP deaminase-dUTPase from Mycobacterium tuberculosis in complex with dTTP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE	polymer	190	20919.7	12	UniProt (O07247) Pfam (PF00692) UniProt (by SIFTS) (P9WP17) In PDB	MYCOBACTERIUM TUBERCULOSIS	DCTP DEAMINASE, DCTP DEAMNIASE-DUTPASE
2	H, I, J, K, L...	THYMIDINE-5'-TRIPHOSPHATE	non-polymer		482.2	12	Chemie (TTP)
3	G, H, I, J, K...	MAGNESIUM ION	non-polymer		24.3	14	Chemie (MG)
4		water	water		18.0	12	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 1 - 190 (UniProt: O07247)

PDB	External Database	Details
Val 115	Ala 115	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	251035.9
Non-Polymers*	Number of molecules	26
	Total formula weight	6126.3
All*	Total formula weight	257162.2

*Water molecules are not included.