3ZBG

Crystal structure of wild-type SCP2 thiolase from Leishmania mexicana at 1.85 A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	3-KETOACYL-COA THIOLASE-LIKE PROTEIN	polymer	457	49306.0	2	UniProt (E9AW84) Pfam (PF00108) Pfam (PF02803) In PDB	LEISHMANIA MEXICANA	SCP2 THIOLASE
2	A, B	DIMETHYL SULFOXIDE	non-polymer		78.1	14	Chemie (DMS)
3	A, B	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	4	Chemie (MPD)
4		water	water		18.0	569	Chemie (HOH)

Sequence modifications

A, B: 1 - 441 (UniProt: E9AW84)

PDB	External Database	Details
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Leu 6	Met 6	SEE REMARK 999
Pro 31	Lys 31	SEE REMARK 999
Ile 34	Val 34	SEE REMARK 999
Lys 45	Gln 45	SEE REMARK 999
Met 61	Ile 61	SEE REMARK 999
His 63	Asn 63	SEE REMARK 999
Ser 64	Val 64	SEE REMARK 999
Ser 67	Lys 67	SEE REMARK 999
Arg 69	Lys 69	SEE REMARK 999
Ser 107	Ala 107	SEE REMARK 999
Met 112	Ile 112	SEE REMARK 999
Met 134	Thr 134	SEE REMARK 999
Ser 139	Ala 139	SEE REMARK 999
Thr 145	Val 145	SEE REMARK 999
Ser 157	Thr 157	SEE REMARK 999
Gln 176	Lys 176	SEE REMARK 999
Thr 229	Ser 229	SEE REMARK 999
Val 268	Ala 268	SEE REMARK 999
Arg 277	Lys 277	SEE REMARK 999
Ile 327	Val 327	SEE REMARK 999
Glu 356	Asp 356	SEE REMARK 999
Asp 368	Glu 368	SEE REMARK 999
Ile 398	Val 398	SEE REMARK 999
Glu 410	Gly 410	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	98612.0
Non-Polymers*	Number of molecules	18
	Total formula weight	1566.6
All*	Total formula weight	100178.5

*Water molecules are not included.