3WYF
Crystal structure of Xpo1p-Yrb2p-Gsp1p-GTP complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D | Gsp1p | polymer | 219 | 24825.4 | 2 | UniProt (E7KFU1) In PDB | Saccharomyces cerevisiae AWRI796 (Baker's yeast) | |
| 2 | B, E | Ran-specific GTPase-activating protein 2 | polymer | 238 | 26237.6 | 2 | UniProt (P40517) Pfam (PF00638) In PDB | Saccharomyces cerevisiae S288c (Baker's yeast) | Ran-binding protein 2, RANBP2 |
| 3 | C, F | Exportin-1 | polymer | 1049 | 120398.2 | 2 | UniProt (P30822) Pfam (PF03810) Pfam (PF08389) Pfam (PF18777) Pfam (PF18784) Pfam (PF18787) Pfam (PF08767) In PDB | Saccharomyces cerevisiae S288c (Baker's yeast) | Chromosome region maintenance protein 1, Karyopherin-124 |
| 4 | A, D | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 5 | A, D | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | water | water | 18.0 | 888 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 219 (UniProt: E7KFU1)
C, F: 1 - 1084 (UniProt: P30822)
| PDB | External Database | Details |
|---|---|---|
| Leu 71 | Gln 71 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| - | Val 377 | deletion |
| - | Gln 378 | deletion |
| - | Arg 379 | deletion |
| - | Leu 380 | deletion |
| - | Pro 381 | deletion |
| - | Ala 382 | deletion |
| - | Thr 383 | deletion |
| - | Glu 384 | deletion |
| - | Met 385 | deletion |
| - | Ser 386 | deletion |
| - | Pro 387 | deletion |
| - | Leu 388 | deletion |
| - | Ile 389 | deletion |
| - | Gln 390 | deletion |
| - | Leu 391 | deletion |
| - | Ser 392 | deletion |
| - | Val 393 | deletion |
| - | Gly 394 | deletion |
| - | Ser 395 | deletion |
| - | Gln 396 | deletion |
| - | Ala 397 | deletion |
| - | Ile 398 | deletion |
| - | Ser 399 | deletion |
| - | Thr 400 | deletion |
| - | Gly 401 | deletion |
| - | Ser 402 | deletion |
| - | Gly 403 | deletion |
| - | Ala 404 | deletion |
| - | Leu 405 | deletion |
| - | Asn 406 | deletion |
| - | Pro 407 | deletion |
| - | Glu 408 | deletion |
| - | Tyr 409 | deletion |
| - | Met 410 | deletion |
| - | Lys 411 | deletion |
| - | Arg 412 | deletion |
| - | Phe 413 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 342922.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1095.0 | |
| All* | Total formula weight | 344017.4 |
