3WTP
Crystal Structure of the heterotypic nucleosome containing human CENP-A and H3.3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Histone H3-like centromeric protein A | polymer | 143 | 16305.9 | 1 | UniProt (P49450) Pfam (PF00125) In PDB | Homo sapiens (human) | Centromere autoantigen A, Centromere protein A, CENP-A |
2 | B, F | Histone H4 | polymer | 106 | 11676.7 | 2 | UniProt (P62805) Pfam (PF15511) In PDB | Homo sapiens (human) | |
3 | C, G | Histone H2A type 1-B/E | polymer | 133 | 14447.8 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) In PDB | Homo sapiens (human) | Histone H2A.2, Histone H2A/a, Histone H2A/m |
4 | D, H | Histone H2B type 1-J | polymer | 129 | 14217.5 | 2 | UniProt (P06899) Pfam (PF00125) In PDB | Homo sapiens (human) | Histone H2B.1, Histone H2B.r, H2B/r |
5 | E | Histone H3.3 | polymer | 140 | 15710.4 | 1 | UniProt (P84243) Pfam (PF00125) In PDB | Homo sapiens (human) | |
6 | I, J | DNA (146-MER) | polymer | 146 | 45053.9 | 2 | Homo sapiens |
Sequence modifications
A: 1 - 140 (UniProt: P49450)
B, F: 0 - 102 (UniProt: P62805)
C, G: 0 - 129 (UniProt: P04908)
D, H: 0 - 125 (UniProt: P06899)
E: 0 - 135 (UniProt: P84243)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Pro -3 | - | expression tag |
Gly -2 | - | expression tag |
His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 202808.1 | |
All* | Total formula weight | 202808.1 |