3VN2
Crystal Structure of PPARgamma complexed with Telmisartan
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Peroxisome proliferator-activated receptor gamma | polymer | 285 | 32493.6 | 1 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-gamma, Nuclear receptor subfamily 1 group C member 3 |
| 2 | C | Nuclear receptor coactivator 1 | polymer | 16 | 1905.2 | 1 | UniProt (Q15788) In PDB | Homo sapiens | NCoA-1, Class E basic helix-loop-helix protein 74, bHLHe74, Protein Hin-2, RIP160, Renal carcinoma antigen NY-REN-52, Steroid receptor coactivator 1, SRC-1 |
| 3 | A | 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid | non-polymer | 514.6 | 1 | Chemie (TLS) | |||
| 4 | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
A: 197 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 193 | - | expression tag |
| Ser 194 | - | expression tag |
| His 195 | - | expression tag |
| Met 196 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34398.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 514.6 | |
| All* | Total formula weight | 34913.4 |
