3UX0
Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilizer Fusicoccin H
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 14-3-3 protein sigma | polymer | 235 | 26501.9 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (human) | Epithelial cell marker protein 1, Stratifin |
2 | P | TASK3 PHOSPHOPEPTIDE | polymer | 6 | 857.0 | 1 | UniProt (Q9NPC2) In PDB | Homo sapiens | |
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
6 | A | (4R,5R,6R,6aS,9S,9aE,10aR)-5-hydroxy-9-(hydroxymethyl)-6,10a-dimethyl-3-(propan-2-yl)-1,2,4,5,6,6a,7,8,9,10a-decahydrodicyclopenta[a,d][8]annulen-4-yl alpha-D-gulopyranoside | non-polymer | 482.6 | 1 | Chemie (0DV) | |||
7 | water | water | 18.0 | 333 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDB | External Database | Details |
---|---|---|
Ala -3 | - | EXPRESSION TAG |
Met -2 | - | EXPRESSION TAG |
Gly -1 | - | EXPRESSION TAG |
Ser 0 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27358.8 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 707.4 | |
All* | Total formula weight | 28066.2 |