3TU4
Crystal structure of the Sir3 BAH domain in complex with a nucleosome core particle.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E | Histone H3.2 | polymer | 135 | 15303.9 | 2 | UniProt (P84233) Pfam (PF00125) In PDB | Xenopus laevis (clawed frog common platanna platanna) | |
2 | B, F | Histone H4 | polymer | 102 | 11263.2 | 2 | UniProt (P62799) Pfam (PF15511) In PDB | Xenopus laevis (clawed frog common platanna platanna) | |
3 | C, G | Histone H2A | polymer | 129 | 13978.2 | 2 | UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) In PDB | Xenopus laevis (clawed frog common platanna platanna) | |
4 | D, H | Histone H2B 1.1 | polymer | 122 | 13524.8 | 2 | UniProt (P02281) Pfam (PF00125) In PDB | Xenopus laevis (clawed frog common platanna platanna) | H2B1.1 |
5 | I | DNA (146-MER) | polymer | 147 | 45137.8 | 1 | |||
6 | J | DNA (146-MER) | polymer | 147 | 45609.1 | 1 | |||
7 | K, L | Regulatory protein SIR3 | polymer | 229 | 27263.9 | 2 | UniProt (P06701) Pfam (PF01426) In PDB | Saccharomyces cerevisiae S288c (Baker's yeast) | Silent information regulator 3 |
Sequence modifications
A, E: 1 - 135 (UniProt: P84233)
D, H: 1 - 122 (UniProt: P02281)
K, L: 1 - 213 (UniProt: P06701)
PDB | External Database | Details |
---|---|---|
Ala 102 | Gly 103 | conflict |
PDB | External Database | Details |
---|---|---|
Thr 29 | Ser 33 | conflict |
PDB | External Database | Details |
---|---|---|
Asn 205 | Asp 205 | engineered mutation |
Ser 214 | - | expression tag |
Val 215 | - | expression tag |
Asp 216 | - | expression tag |
Lys 217 | - | expression tag |
Leu 218 | - | expression tag |
Ala 219 | - | expression tag |
Ala 220 | - | expression tag |
Ala 221 | - | expression tag |
Leu 222 | - | expression tag |
Glu 223 | - | expression tag |
His 224 | - | expression tag |
His 225 | - | expression tag |
His 226 | - | expression tag |
His 227 | - | expression tag |
His 228 | - | expression tag |
His 229 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 253415.0 | |
All* | Total formula weight | 253415.0 |