3TT1
Crystal Structure of LeuT in the outward-open conformation in complex with Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Leucine transporter LeuT | polymer | 519 | 58003.3 | 2 | UniProt (O67854) Pfam (PF00209) In PDB | Aquifex aeolicus | |
2 | L, M | mouse monoclonal 1gG2a Fab fragment, heavy chain | polymer | 218 | 23911.1 | 2 | Mus musculus (mouse) | ||
3 | H, I | mouse monoclonal 1gG2a Fab fragment, kappa light chain | polymer | 219 | 23575.4 | 2 | Mus musculus | ||
4 | A, B | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
5 | A, B | octyl 1-thio-beta-D-glucopyranoside | non-polymer | 308.4 | 5 | Chemie (SOG) | |||
6 | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 513 (UniProt: O67854)
PDB | External Database | Details |
---|---|---|
Phe 108 | Tyr 108 | engineered mutation |
Ala 288 | Lys 288 | engineered mutation |
Gly 514 | - | expression tag |
Thr 515 | - | expression tag |
Leu 516 | - | expression tag |
Val 517 | - | expression tag |
Pro 518 | - | expression tag |
Arg 519 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 210979.7 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1634.1 | |
All* | Total formula weight | 212613.8 |