3TQ3
Crystal structure of M-PMV dUTPase with a mixed population of substrate (dUPNPP) and post-inversion product (dUMP) in the active sites
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDO HYDROLASE | polymer | 152 | 16155.4 | 1 | UniProt (O92810) Pfam (PF00692) UniProt (by SIFTS) (P07570) In PDB | Mason-Pfizer monkey virus (MPMV) | |
| 2 | A | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 1 | Chemie (UMP) | |||
| 3 | A | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE | non-polymer | 467.2 | 1 | Chemie (DUP) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A: 1 - 152 (UniProt: O92810)
| PDB | External Database | Details |
|---|---|---|
| Lys 1 | Asn 608 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16155.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 799.6 | |
| All* | Total formula weight | 16955.0 |
