3T9H

Kainate bound to a double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, D, F	Glutamate receptor 2	polymer	258	28883.5	3	UniProt (P19491) Pfam (PF10613) Pfam (PF00060) Pfam (PF00497) In PDB	Rattus norvegicus (rat)	GluA2, GluR2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2
2	B, D, F	3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE	non-polymer		213.2	3	Chemie (KAI)
3	B, D, F	ZINC ION	non-polymer		65.4	5	Chemie (ZN)
4		water	water		18.0	571	Chemie (HOH)

Sequence modifications

B, D, F: 4 - 117 (UniProt: P19491)

PDB	External Database	Details
Cys 63	Ala 473	engineered mutation

B, D, F: 120 - 261 (UniProt: P19491)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker
Cys 140	Ser 673	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	86650.4
Non-Polymers*	Number of molecules	8
	Total formula weight	966.7
All*	Total formula weight	87617.1

*Water molecules are not included.