3SFU

crystal structure of murine norovirus RNA dependent RNA polymerase in complex with ribavirin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	RNA polymerase	polymer	517	58519.5	3	UniProt (Q80J95) Pfam (PF00680) In PDB	Murine norovirus 1
2	A, C, B	1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide	non-polymer		244.2	3	Chemie (RBV)
3	B, C, A	SULFATE ION	non-polymer		96.1	27	Chemie (SO4)
4	B, A, C	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
5	C, B, A	GLYCEROL	non-polymer		92.1	26	Chemie (GOL)
6		water	water		18.0	483	Chemie (HOH)

Sequence modifications

A, B, C: 4 - 509 (UniProt: Q80J95)

PDB	External Database	Details
Ala 510	-	EXPRESSION TAG
Ala 511	-	EXPRESSION TAG
Ala 512	-	EXPRESSION TAG
Leu 513	-	EXPRESSION TAG
Glu 514	-	EXPRESSION TAG
His 515	-	EXPRESSION TAG
His 516	-	EXPRESSION TAG
His 517	-	EXPRESSION TAG
His 518	-	EXPRESSION TAG
His 519	-	EXPRESSION TAG
His 520	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	175558.6
Non-Polymers*	Number of molecules	59
	Total formula weight	5793.7
All*	Total formula weight	181352.3

*Water molecules are not included.