3S8Z

Crystal structure of LRP6-E3E4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Low-density lipoprotein receptor-related protein 6	polymer	623	70828.7	1	UniProt (O75581) Pfam (PF00058) Pfam (PF14670) In PDB	Homo sapiens (human)	LRP-6
2	B	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
3	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A: 629 - 1243 (UniProt: O75581)

PDB	External Database	Details
His 621	-	expression tag
His 622	-	expression tag
His 623	-	expression tag
His 624	-	expression tag
His 625	-	expression tag
His 626	-	expression tag
His 627	-	expression tag
His 628	-	expression tag
Ile 1062	Val 1062	variant

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	70828.7
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	71916.8

*Water molecules are not included.