3S6Y
Structure of reovirus attachment protein sigma1 in complex with alpha-2,6-sialyllactose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Outer capsid protein sigma-1 | polymer | 325 | 35360.8 | 3 | UniProt (P03528) Pfam (PF01664) In PDB | Reovirus type 3 (Mammalian orthoreovirus 3) | Sigma1, Cell attachment protein, Hemagglutinin |
| 2 | D, E | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 633.6 | 2 | In PDB BIRD (PRD_900066) GlyTouCan (G28868ZC) | 6'-sialyl-lactose | ||
| 3 | B | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 1 | Chemie (SIA) | |||
| 4 | water | water | 18.0 | 429 | Chemie (HOH) |
Sequence modifications
A, B, C: 170 - 455 (UniProt: P03528)
| PDB | External Database | Details |
|---|---|---|
| Gln 131 | - | expression tag |
| Ile 132 | - | expression tag |
| Glu 133 | - | expression tag |
| Asp 134 | - | expression tag |
| Lys 135 | - | expression tag |
| Ile 136 | - | expression tag |
| Glu 137 | - | expression tag |
| Glu 138 | - | expression tag |
| Ile 139 | - | expression tag |
| Leu 140 | - | expression tag |
| Ser 141 | - | expression tag |
| Lys 142 | - | expression tag |
| Ile 143 | - | expression tag |
| Tyr 144 | - | expression tag |
| His 145 | - | expression tag |
| Ile 146 | - | expression tag |
| Glu 147 | - | expression tag |
| Asn 148 | - | expression tag |
| Glu 149 | - | expression tag |
| Ile 150 | - | expression tag |
| Ala 151 | - | expression tag |
| Arg 152 | - | expression tag |
| Ile 153 | - | expression tag |
| Lys 154 | - | expression tag |
| Lys 155 | - | expression tag |
| Leu 156 | - | expression tag |
| Ile 157 | - | expression tag |
| Gly 158 | - | expression tag |
| Glu 159 | - | expression tag |
| Gly 160 | - | expression tag |
| Ser 161 | - | expression tag |
| Gly 162 | - | expression tag |
| Arg 163 | - | expression tag |
| Pro 164 | - | expression tag |
| Val 165 | - | expression tag |
| Leu 166 | - | expression tag |
| Asn 167 | - | expression tag |
| Gln 168 | - | expression tag |
| Gly 169 | - | expression tag |
| Ile 249 | Thr 249 | engineered mutation |
| Thr 408 | Ala 408 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 106082.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1267.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 309.3 | |
| All* | Total formula weight | 107658.7 |
