3QKP
Protein Tyrosine Phosphatase 1B - Apo W179F mutant with open WPD-loop
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 321 | 37326.6 | 1 | UniProt (P18031) Pfam (PF00102) In PDB | Homo sapiens (human) | Protein-tyrosine phosphatase 1B, PTP-1B |
| 2 | A | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 239 | Chemie (HOH) |
Sequence modifications
A: 1 - 321 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Phe 179 | Trp 179 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37326.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 306.3 | |
| All* | Total formula weight | 37632.9 |
